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Microsoft Office 2010 64-bit is now certified with EBS 12.0.6, 12.1.3, and 12.2 with desktop clients using the following configurations:

• Windows 7 64-bit
  • Internet Explorer 8 (64-bit)
  • Internet Explorer 9 (64-bit)
  • Internet Explorer 10 (64-bit)
• Windows 8 64-bit
  • Internet Explorer 10 (64-bit)

The 32-bit equivalents are already certified; details are available here.
Are any patches required?

You must apply server-side patches to EBS 12.0.6 and 12.1.3 environments. Additional server-side patches are not required for EBS 12.2.x. All required interop patches are documented here:

• Using Microsoft Office 2007 and 2010 with Oracle E-Business Suite 11i and R12 (Note 1077728.1)